The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2014

Filed:

Jul. 13, 2012
Applicants:

Jih RU Hwu, Hsinchu, TW;

Yu-sern Lin, Hsinchu, TW;

Chen-sheng Yeh, Hsinchu, TW;

Dar-bin Shieh, Tainan, TW;

Wu-chou Su, Tainan, TW;

Inventors:

Jih Ru Hwu, Hsinchu, TW;

Yu-Sern Lin, Hsinchu, TW;

Chen-Sheng Yeh, Hsinchu, TW;

Dar-Bin Shieh, Tainan, TW;

Wu-Chou Su, Tainan, TW;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 493/00 (2006.01); A61K 38/00 (2006.01); A61K 9/16 (2006.01); C07F 9/6558 (2006.01); A61K 47/48 (2006.01); A61K 31/665 (2006.01); C07F 9/655 (2006.01);
U.S. Cl.
CPC ...
C07F 9/65512 (2013.01); C07F 9/65586 (2013.01); A61K 47/48861 (2013.01); A61K 31/665 (2013.01);
Abstract

A phosphate-containing nanoparticle delivery vehicle includes nanoparticle, an active ingredient, and a phosphodiester moiety connecting the nanoparticle and the active ingredient and forms a prodrug. The nanoparticle delivery vehicle achieves the function of increasing hydrophilicity of the active ingredient and specificity against tumor cells. Advantages of the nanoparticle material include biocompatibility, magnetism and/or controllable drug release.


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