Company Filing History:
Years Active: 2012-2020
Title: Innovations in Baclofen Formulations by Inventor Jianwei Li
Introduction
Jianwei Li, an accomplished inventor based in Woodbury, MN, has made significant contributions to the field of pharmacology, particularly through his work on baclofen formulations. With 8 patents to his name, Li has developed innovative methods for creating and using baclofen, a medication primarily used to treat muscle spasticity and various neurological conditions.
Latest Patents
Li’s most recent patents focus on advanced formulations and preparation methods for baclofen solutions. One of his notable inventions details methods for preparing sterilized baclofen solutions, which involves adjusting the pH below a desired level and steam sterilizing the solution. This process ensures that the solution attains the intended pH and contains low concentrations of 4-CPP. His injectable baclofen solutions, with concentrations exceeding 2 mg/mL, are designed to include phosphate or sulfate species in the range of 5 mM to 25 mM. These formulations have an ionic strength comparable to approximately 1.5 M NaCl. In his patent applications, Li outlines baclofen formulations intended for treating conditions such as spasticity, brain injury, cerebral palsy, spinal cord injury, cervical injury, multiple sclerosis, thoracic injury, and withdrawal symptoms.
Career Highlights
Throughout his career, Jianwei Li has worked with reputed organizations, including Saol International Limited and Medtronic, Inc. His involvement in these companies has enhanced his expertise and facilitated the development of groundbreaking innovations in baclofen solutions.
Collaborations
Li's endeavors have been complemented by fruitful collaborations with esteemed colleagues, including Deanna S Lane and Lanchi T Le. These partnerships have undoubtedly enriched his research and broadened the impact of his inventions in the pharmaceutical domain.
Conclusion
Jianwei Li's innovative work on baclofen formulations illustrates the vital role of inventors in advancing medical science. His patents not only highlight his skills as an inventor but also demonstrate a commitment to improving treatments for complex neurological conditions, thereby enhancing patient care and treatment outcomes.