The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2016

Filed:

Oct. 04, 2011
Applicants:

Deanna S. Lane, Golden Valley, MN (US);

Charlene X. Yuan, Woodbury, MN (US);

Jianwei LI, Woodbury, MN (US);

Lanchi T. Le, Lake Elmo, MN (US);

Inventors:

Deanna S. Lane, Golden Valley, MN (US);

Charlene X. Yuan, Woodbury, MN (US);

Jianwei Li, Woodbury, MN (US);

Lanchi T. Le, Lake Elmo, MN (US);

Assignee:

Medtronic, Inc., Minneapolis, MN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 47/26 (2006.01); A61K 38/00 (2006.01); A61K 38/19 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0019 (2013.01); A61K 47/26 (2013.01);
Abstract

A formulation for use in an implantable infusion device includes between about 5 mg/ml and about 500 mg/ml (e.g., about 10-25 mg/ml) of a TNF inhibitor polypeptide, 10 mM-25 mM of a phosphate or citrate buffer, has an ionic strength of the combined buffer and an optional salt of the equivalent of about 0.1-0.2 NaCl (e.g., about 0.15 M), 5% to 10% of a carbohydrate (e.g., trehalose or sucrose), has a pH of between 6 and 7, is fluid at room temperature and at 37° C., and has a viscosity of less than about 10 centipoise (e.g., between about 1 centipoise and 9 centipoise, between about 1 cp and about 5 cp, between about 1 cp and about 3 cp, or between about 1 cp and about 2.5 cp) at room temperature.


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Quick Actions:

Lane, Deanna. (2016). Tnf inhibitor formulation for use in implantable infusion devices (U.S. Patent No. 9445990). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9445990

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