Jiankai Liu

Title: Innovations and Contributions of Inventor Jiankai Liu

Introduction

Jiankai Liu is a notable inventor based in Beijing, China, known for his significant contributions to biotechnology and virology. With a total of three patents, his work focuses on the development of innovative methods related to virus-like particles and vaccines.

Latest Patents

One of Jiankai Liu's latest patents is titled "Engineered Hansenula Fungi Efficiently Expressing CA10 Virus-Like Particles and Uses Thereof." This patent describes an engineered fungus that efficiently expresses CA10 (Coxsackievirus A10) virus-like particles. It includes a recombinant vector that carries the P1 and 3CD genes of the CA10 virus, optimized for preferred codons. Additionally, the patent outlines a preparation method for CA10 virus-like particles and the vaccines derived from them.

Another significant patent from Liu is "Purification of Recombinant EV71 Virus-Like Particle and Method for Preparing Vaccine Thereof." This invention provides a detailed method for purifying an EV71 virus-like particle. The process includes high-density fermentation cultivation of recombinantly engineered bacteria, inducing protein expression using methanol, and various purification techniques such as ion exchange chromatography and molecular sieve chromatography.

Career Highlights

Jiankai Liu currently works at Beijing Minhai Biotechnology Co., Ltd., where he is actively involved in researching and developing biotechnological solutions. His expertise and innovative approaches have led to advancements in vaccine production and virus-like particle expression, which hold promising implications for public health.

Collaborations

In his work, Liu collaborates with notable colleagues such as Guoshun Li and Meirong Gu. These partnerships enhance the scope and impact of their collective research, driving forward advancements in biotechnology.

Conclusion

Jiankai Liu's inventive work in the field of biotechnology and his patent contributions demonstrate his commitment to enhancing medical solutions and vaccine development. His innovative approaches are likely to play a vital role in addressing viral diseases and improving public health outcomes in the future.