Jesse J Twu

Title: Jesse J Twu: Innovator in Fluorescent pH Indicators

Introduction

Jesse J Twu is a notable inventor based in Cupertino, CA (US). He has made significant contributions to the field of intracellular assays through his innovative work on fluorescent pH indicators. With a total of 2 patents, his inventions have the potential to enhance the accuracy of pH measurements in biological samples.

Latest Patents

Jesse J Twu's latest patents focus on methods of using fluorescent pH indicators for intracellular assays. These systems include compositions and methods for measuring pH, particularly in cells, organelles, and other samples. The compositions consist of pH-sensitive fluorescent and fluorogenic 2',7′-dialkylfluorescein derivatives and associated nonfluorescent precursor compounds. These innovations allow for ratiometric measurement in both the excitation and emission spectra. The methods involve adding a precursor compound to a sample cell, incubating the sample cell to release the free indicator, illuminating the sample cell, and detecting the fluorescence response of the free indicator.

Career Highlights

Throughout his career, Jesse has worked with prominent companies such as Molecular Devices Corporation and MDS Analytical Technologies (US) Inc. His experience in these organizations has contributed to his expertise in developing advanced measurement systems.

Collaborations

Jesse has collaborated with talented individuals in his field, including Zhenjun Diwu and Guoliang Yi. These partnerships have likely fostered innovation and creativity in his work.

Conclusion

Jesse J Twu's contributions to the field of fluorescent pH indicators demonstrate his commitment to advancing scientific research and technology. His innovative patents and collaborations highlight his role as a significant inventor in the industry.