Jens H Gundlach

Title: The Innovative Contributions of Jens H. Gundlach

Introduction

Jens H. Gundlach, based in Seattle, WA, is a prolific inventor with an impressive portfolio of 32 patents. His work primarily focuses on advanced techniques in nanopore-based analysis, contributing significantly to the fields of biochemistry and molecular biology.

Latest Patents

One of his latest patents involves "Nanopore-based analysis of protein characteristics." This groundbreaking method provides insights into the characterization of target protein analytes that exceed the internal diameter of the nanopore tunnel and are physically associated with polymers. By applying an electrical potential to the nanopore system, he allows for interactions between the polymer and the nanopore tunnel. The measurement of ion currents through the nanopore reveals current patterns indicative of the polymer's structure, offering crucial information for characterizing associated proteins that cannot pass through the nanopore.

Another notable patent is for "Methods and compositions for generating reference maps for nanopore-based polymer analysis." This innovation details the creation of reference signals for polymer analysis in nanopore systems with multi-subunit output signal resolution. The method involves translocating a unique reference sequence through a nanopore to produce various reference output signals, which are then compiled into a reference map for effective nanopore analysis of an analyte polymer. Additionally, the patent includes methods for calibrating the nanopore system to optimize polymer analysis.

Career Highlights

Jens H. Gundlach has made significant strides in his career, holding positions at the University of Washington and Illumina Corporation. His research and development work in these leading institutions has been instrumental in advancing nanopore technology, particularly in protein and polymer analysis.

Collaborations

Throughout his career, Gundlach has collaborated with esteemed colleagues including Ian M. Derrington and Andrew Laszlo. These collaborations have fostered an environment of innovation, resulting in significant advancements in nanopore-based technologies.

Conclusion

Jens H. Gundlach stands out as a key inventor in the realm of nanopore technology. His patents not only demonstrate his innovative spirit but also pave the way for practical applications in scientific research. His ongoing contributions continue to shape the future of molecular analysis, benefiting academia and industry alike.