Jeng-Horng Her

Title: The Innovative Journey of Jeng-Horng Her

Introduction

Jeng-Horng Her, a prolific inventor based in San Jose, California, has made significant contributions to the field of biotechnology. With 13 patents to his name, his work focuses primarily on developing cutting-edge therapeutic solutions for cancer treatment. His innovative approach combines the principles of molecular engineering and immunotherapy, reflecting his commitment to advancing medical science.

Latest Patents

Among Jeng-Horng Her's latest patents are groundbreaking inventions that showcase his expertise in bispecific proteins and antibody-drug conjugates. One of his notable patents is for bifunctional proteins combining checkpoint blockade for targeted therapy. This invention provides bispecific proteins that encompass a binding domain targeting cell surface proteins, along with a vascular endothelial growth factor (VEGF) inhibiting domain. Additionally, his work includes an antibody-drug conjugate featuring a therapeutic agent covalently conjugated to an antibody or an antigen-binding fragment that binds to PD-L1 and/or a VEGF inhibiting domain.

Another important patent in his portfolio revolves around CD137 antibodies for T-cell activation. This patent describes antibodies that have an antigen-binding region binding to CD137, as well as bispecific antibodies comprising a first antigen-binding region that connects to CD137 and a second region binding to immune checkpoint molecules, immune stimulatory molecules, or tumor antigens. The patent also provides pharmaceutical compositions featuring these antibodies and methods for treating cancer, solidifying his significant role in oncology innovation.

Career Highlights

Jeng-Horng Her has been affiliated with several prominent companies in the biotechnology field, including Ap Biosciences Inc. and KaloBios Pharmaceuticals, Inc. His experience at these companies has allowed him to collaborate with experts and contribute to pioneering research that bridges the gap between laboratory discoveries and clinical applications.

Collaborations

In his pursuit of innovation, Jeng-Horng Her has collaborated with talented professionals, including Robert F. Balint and Ching-Hsuan Hsu. These partnerships demonstrate the importance of teamwork in driving scientific advancements and developing new therapeutic methodologies in cancer treatment.

Conclusion

Jeng-Horng Her's diverse portfolio of patents and his collaborative spirit have positioned him as a key figure in the field of biotechnology. His innovative inventions hold great promise for transforming cancer therapies and improving patient outcomes. As he continues to push the boundaries of medical research, Jeng-Horng Her remains an inspiring inventor dedicated to making a lasting impact on healthcare.