The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2011
Filed:
Jan. 20, 2005
Peter Flynn, San Francisco, CA (US);
Kenneth Luehrsen, Half Moon Bay, CA (US);
Robert F. Balint, Palo Alto, CA (US);
Jeng-horng Her, San Jose, CA (US);
Christopher R. Bebbington, San Mateo, CA (US);
Geoffrey T. Yarranton, Burlingame, CA (US);
Peter Flynn, San Francisco, CA (US);
Kenneth Luehrsen, Half Moon Bay, CA (US);
Robert F. Balint, Palo Alto, CA (US);
Jeng-Horng Her, San Jose, CA (US);
Christopher R. Bebbington, San Mateo, CA (US);
Geoffrey T. Yarranton, Burlingame, CA (US);
KaloBios Pharmaceuticals, Inc., South San Francisco, CA (US);
Abstract
The present invention provides methods of making antibodies having the binding specificity of a reference antibody. Antibodies generated by the methods of the inventions have at least one minimal essential binding specificity determinant from a heavy chain or light chain CDR3 from the reference antibody. The method can be used, e.g., in humanization procedures. The invention also provides libraries and antibodies made in accordance with the methods.