The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2022
Filed:
Mar. 10, 2016
Applicants:
Allgenesis Biotherapeutics Inc., Taipei, TW;
Ap Biosciences, Inc., Taipei, TW;
Inventors:
Kevin Zen, Del Mar, CA (US);
Pei-Tzu Wu, Taipei, TW;
Jeng-Horng Her, Taipei, TW;
Huang-Tsu Chen, Taipei, TW;
Jiun-Shyang Leou, Taipei, TW;
Ching-Hsuan Hsu, Taipei, TW;
Assignees:
Allgenesis Biotherapeutics Inc., Taipei, TW;
AP Biosciences Inc., Taipei, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); C07K 14/71 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/71 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01); C07K 2319/70 (2013.01);
Abstract
Fusion proteins containing a PDGF binding portion, a VEGF binding portion, and an Fc antibody region are described. Also described are nucleic acids encoding the fusion proteins, compositions comprising the fusion proteins, and methods of using the fusion proteins for treating or preventing clinical conditions characterized by abnormal angiogenesis, such as vascular permeability, edema or inflammation.