Location History:
- Madison, CT (US) (2008)
- Seattle, WA (US) (1999 - 2011)
- Woodinville, WA (US) (2012 - 2023)
Company Filing History:
10 out of 451 
4 out of 1,970 
4 out of 13 
Years Active: 1999-2023
Title: Jeffrey T. McGrew: Innovator in Recombinant Expression Technology
Introduction
Jeffrey T. McGrew, located in Seattle, WA, has established himself as a noteworthy innovator in the field of recombinant expression technology. With 19 patents to his name, McGrew’s contributions are crucial for advancements in protein production and genetic engineering.
Latest Patents
Two of his most recent patents focus on recombinant expression vectors derived from transposon-based systems. The first patent, “Expression from Transposon-Based Vectors and Uses,” discloses vectors that merge a mCMV enhancer sequence with a rat EF-1alpha intron sequence for the recombinant expression of proteins. These vectors are particularly valuable for tetracycline-inducible expression, featuring both a 5' and a 3' PiggyBac ITR to facilitate genomic integration into host cell chromosomes. Additionally, the patent outlines a method for selecting stable production cell lines for the manufacturing of proteins of interest.
The second patent, “Inducible Expression from Transposon-Based Vectors and Uses,” shares similar constructs and applications, reinforcing the utility of these innovative vectors in mammalian host cells. It presents a method for producing proteins in vitro, further showcasing McGrew's expertise in transforming genetic engineering practices.
Career Highlights
Throughout his career, Jeffrey McGrew has worked with prominent organizations, including Immunex Corporation and Just-evotec Biologics, Inc. His work in these companies has enhanced their capabilities in biotechnological applications and therapeutic developments, greatly impacting the field.
Collaborations
McGrew has collaborated with talented individuals like Pauline S. Smidt and E-Ching Ong. These partnerships signify the vibrant and innovative environment in which he has contributed to advancing recombinant technology.
Conclusion
Jeffrey T. McGrew's impressive portfolio of 19 patents and collaborations reflect his significant role in modern biotechnology. His innovations in recombinant expression vectors present valuable tools for protein production, paving the way for advancements in therapeutic applications and genetic research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.