Location History:
- King County, WA (US) (1991 - 1996)
- Seattle, WA (US) (1992 - 1997)
Company Filing History:
Years Active: 1991-1997
Title: The Innovations of Jeffrey N Fitzner
Introduction
Jeffrey N Fitzner is a notable inventor based in Seattle, WA (US). He has made significant contributions to the field of biochemistry, particularly in the development of compounds that inhibit the secretion of TNF-.alpha. His work has led to the issuance of 9 patents, showcasing his innovative approach to solving complex biological problems.
Latest Patents
Fitzner's latest patents focus on inhibitors of TNF-.alpha. secretion. These patents disclose compounds and methods that are useful in inhibiting the TNF-.alpha. converting enzyme (TACE), which is responsible for the cleavage of TNF-.alpha. precursor to provide biologically active TNF-.alpha. The compounds employed in this invention are peptidyl derivatives that possess active groups capable of inhibiting TACE, such as hydroxamates, thiols, phosphoryls, and carboxyls.
Career Highlights
Throughout his career, Fitzner has worked with prominent companies in the biotechnology sector, including Neorx Corporation and Immunex Corporation. His experience in these organizations has allowed him to refine his skills and contribute to groundbreaking research in the field.
Collaborations
Fitzner has collaborated with notable professionals in his field, including Ananthachari Srinivasan and Sudhakar Kasina. These collaborations have further enhanced his research and development efforts.
Conclusion
Jeffrey N Fitzner's innovative work in the field of biochemistry has led to significant advancements in the understanding and treatment of diseases related to TNF-.alpha. His contributions, reflected in his 9 patents, continue to impact the scientific community positively.