Company Filing History:
5 out of 8 
4 out of 712 
1 out of 2,480 
Years Active: 1995-2004
Title: Innovations and Contributions of Jeffrey K Pullen
Introduction
Jeffrey K Pullen is a notable inventor based in Columbia, MD (US), recognized for his significant contributions to the field of immunology. He holds a total of six patents, showcasing his innovative approach to vaccine development and protein expression.
Latest Patents
One of his latest patents is titled "Modified immunogenic pneumolysin compositions as vaccines." This invention focuses on modified pneumolysin polypeptides that maintain the immunogenic properties of native pneumolysin while exhibiting reduced or undetectable hemolytic activity. The invention also outlines a method for generating novel pneumolysin variants with these advantageous characteristics. Additionally, it provides immunogenic compositions that can be utilized as pharmaceutical formulations, including vaccines that stimulate protective immunity. Another significant patent is the "Method for the high level expression, purification and refolding of the outer membrane protein P2 from Haemophilus influenzae type b." This invention details a method for expressing the Hib-P2 protein in E. coli, ensuring that it comprises more than 2% of the total protein expressed. It also includes methods for the purification and refolding of the Hib-P2 protein and its fusion proteins.
Career Highlights
Throughout his career, Jeffrey K Pullen has worked with esteemed organizations such as North American Vaccine, Inc. and The Rockefeller University. His work has significantly advanced the understanding and development of vaccines, particularly in the context of pneumolysin and Hib-P2 proteins.
Collaborations
He has collaborated with notable colleagues, including Joseph Y Tai and Shu-Mei Liang, contributing to various research projects and innovations in the field.
Conclusion
Jeffrey K Pullen's innovative work in vaccine development and protein expression has made a lasting impact on immunology. His patents reflect a commitment to advancing medical science and improving public health through effective immunogenic solutions.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.