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Years Active: 2016-2022
Title: The Innovative Contributions of Jeffrey D. Macklis
Introduction
Jeffrey D. Macklis is a prominent inventor based in Brookline, MA (US). He has made significant contributions to the fields of molecular biology and bioengineering. With a total of 2 patents, his work focuses on advancing technologies that have the potential to revolutionize medical and scientific research.
Latest Patents
Macklis's latest patents include groundbreaking inventions. One of his notable patents is titled "Methods and systems of molecular recording by CRISPR-Cas system." This invention provides methods for altering a cell by introducing a nucleic acid sequence encoding a Cas1 protein and/or a Cas2 protein of a CRISPR adaptation system. The invention also includes a CRISPR array nucleic acid sequence that allows for in vivo molecular recordings of events within a cell.
Another significant patent is the "Device for high throughput investigations of multi-cellular interactions." This invention features microfluidic devices that serve as a 3D bioassay for various applications, including drug screening and tissue engineering. The device is designed with channels that can be filled with biologically relevant gels, allowing for the observation of cell growth and interactions in a three-dimensional environment.
Career Highlights
Throughout his career, Jeffrey D. Macklis has worked with esteemed institutions such as the Massachusetts Institute of Technology and The General Hospital Corporation. His work has been instrumental in advancing research in molecular biology and bioengineering.
Collaborations
Macklis has collaborated with notable individuals in his field, including Roger Dale Kamm and Haruhiko Harry Asada. These collaborations have further enriched his research and contributions to science.
Conclusion
Jeffrey D. Macklis is a distinguished inventor whose work in molecular biology and bioengineering has led to significant advancements in the field. His innovative patents and collaborations highlight his commitment to pushing the boundaries of scientific research.