Acton, MA, United States of America

Jason B Cross

USPTO Granted Patents = 9 

 

Average Co-Inventor Count = 6.9

ph-index = 1

Forward Citations = 1(Granted Patents)


Company Filing History:


Years Active: 2014-2015

where 'Filed Patents' based on already Granted Patents

9 patents (USPTO):

Title: **The Innovations of Jason B. Cross: A Pioneer in Antibiotic Development**

Introduction

Jason B. Cross is an accomplished inventor based in Acton, MA, known for his significant contributions to the field of pharmaceutical innovations. With a robust portfolio of nine patents, Cross has emerged as a critical figure in the development of beta-lactamase inhibitors, which play a pivotal role in enhancing the effectiveness of antibiotics against resistant bacterial strains.

Latest Patents

Among his latest inventions are the beta-lactamase inhibitors that feature aryl substituted diazabicyclooctanes (DBO) compounds. These innovative compounds have been designed to inhibit β-lactamases of class A, class C, and class D, thus potentiating the action of β-lactam antibiotics. Specifically, his disclosure introduces DBO compounds that, when used in the Synergy MIC Assay with a β-lactam antibiotic at a fixed concentration, demonstrate a minimum inhibitory concentration (MIC) of 8 µg/mL or less against various isogenic β-lactamase-expressing bacterial strains. This advancement holds substantial implications for treating bacterial infections that have become resistant to standard antibiotic therapies.

Career Highlights

Jason B. Cross has made remarkable strides in his career, particularly in his role at Cubist Pharmaceuticals, Incorporated. His work has not only aided in the development of new pharmacological therapies but has also positioned his company at the forefront of antibiotic research and innovation.

Collaborations

Throughout his career, Cross has worked alongside esteemed colleagues, including Yu Gui Gu and Yong He. This collaborative environment fosters a synergistic approach to research and development, enabling them to tackle complex challenges in antibiotic resistance and enhance product efficacy through innovative methodologies.

Conclusion

Jason B. Cross exemplifies the spirit of innovation with his groundbreaking work in antibiotic development. His patented inventions and collaborations have the potential to significantly impact the pharmaceutical industry and advance the fight against antibiotic-resistant infections. As the landscape of medicine continues to evolve, inventors like Cross play a crucial role in paving the way for future advancements.

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