The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 13, 2015

Filed:

Mar. 29, 2013
Applicant:

Cubist Pharmaceuticals, Inc., Lexington, MA (US);

Inventors:

Yu Gui Gu, Acton, MA (US);

Yong He, Bedford, MA (US);

Ning Yin, Lexington, MA (US);

Dylan C. Alexander, Watertown, MA (US);

Jason B. Cross, Acton, MA (US);

Chester A. Metcalf, III, Needham, MA (US);

Assignee:

Cubist Pharmaceuticals, Inc., Lexington, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/08 (2006.01); A61K 31/546 (2006.01); A61K 31/439 (2006.01); A61K 31/545 (2006.01); A61K 31/407 (2006.01); A61K 45/06 (2006.01); A61K 31/436 (2006.01); A61K 31/427 (2006.01);
U.S. Cl.
CPC ...
A61K 31/546 (2013.01); A61K 31/439 (2013.01); A61K 31/436 (2013.01); C07D 471/08 (2013.01); A61K 31/407 (2013.01); A61K 45/06 (2013.01); A61K 31/427 (2013.01); A61K 31/545 (2013.01);
Abstract

β-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class D β-lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.


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