This inventor holds 4 USPTO granted patents. Top assignees: The United States of America, as Represented by the Secretary, Department of Health and Human Services, Erasmus University Rotterdam. Active years: 2003-2010.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
3 out of 3,699 
1 out of 22 
Years Active: 2003-2010
Title: Jan H J Hoeijmakers: Innovator in DNA Repair and Apoptosis Screening
Introduction
Jan H J Hoeijmakers is a prominent inventor based in Zevenhuizen, Netherlands. He has made significant contributions to the field of molecular biology, particularly in understanding DNA repair mechanisms and apoptosis. With a total of 4 patents, his work has implications for cancer research and genetic disorders.
Latest Patents
One of Hoeijmakers' latest patents involves detection methods based on HR23 protein binding molecules. This method provides a way to determine whether an agent can induce a DNA lesion in a eukaryotic cell. The process includes exposing the cell to the agent and assessing the accumulation of an HR23 protein-binding molecule, such as xeroderma pigmentosum group C (XPC) or 3-methyladenine DNA glycosylase (MAG). This rapid and sensitive test offers significant advantages over traditional methods like the Ames test. Additionally, he has developed methods for determining whether an agent can inhibit cellular processes that lead to the accumulation of HR23 protein-binding molecules. His work also addresses the identification of cells with impaired DNA repair systems, which is crucial for understanding diseases like xeroderma pigmentosum and Cockayne syndrome. Another notable patent focuses on screening assays for compounds that induce apoptosis in tumor cells, providing valuable tools for in vitro diagnosis and treatment development.
Career Highlights
Throughout his career, Jan H J Hoeijmakers has collaborated with esteemed institutions, including the United States Department of Health and Human Services and Erasmus University Rotterdam. His research has been pivotal in advancing our understanding of DNA repair and its implications for human health.
Collaborations
Some of his notable coworkers include Curtis C Harris and Xin Wei Wang, who have contributed to his research endeavors.
Conclusion
Jan H J Hoeijmakers stands out as a key figure in the field of molecular biology, with his innovative patents paving the way for advancements in DNA repair and cancer treatment. His contributions continue to influence research and development in these critical areas.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile