Company Filing History:
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1 out of 832,843 Years Active: 1999-2009
Title: James P. Griffith: Innovator in Tyrosine Kinase Research
Introduction
James P. Griffith, located in Weston, MA, has made significant contributions to the field of biochemistry and molecular biology. With a total of five patents to his name, he is recognized for his innovative work that paves the way for advancements in targeted therapies for diseases such as cancer.
Latest Patents
Among his latest patents is the invention related to the crystal structure of FMS-like tyrosine kinase (FLT3). This patent encompasses the binding pockets of FLT3, providing critical insight into structure coordinates that can be used to identify and design compounds targeting FLT3 and its homologous proteins. His work facilitates the screening for inhibitors that may be vital in treating various malignancies.
Another noteworthy patent from Griffith involves molecules that comprise a calcineurin-like binding pocket. This invention focuses on crystallized molecules that possess active site binding functionalities, offering a data storage interface capable of graphically representing these structures. This innovative approach can assist researchers in developing compounds that interact effectively with calcineurin and its related analogs.
Career Highlights
James P. Griffith’s professional journey has seen him contribute significantly to Vertex Pharmaceuticals, Inc., among other institutions. His expertise in biochemical research has led to groundbreaking innovations that potentially revolutionize therapeutic strategies and drug design.
Collaborations
Throughout his career, Griffith has collaborated with notable professionals in the field, including Keith P. Wilson and Eunice E. Kim. These partnerships have enhanced his research capabilities and contributed to the successful development of his innovative patents.
Conclusion
James P. Griffith's achievements in the realm of innovation are marked by his commitment to exploring and understanding complex biochemical structures and their implications in medicine. His patents not only reflect his deep understanding of molecular biology but also signify the potential impacts of his work on future drug therapies. As he continues to push the boundaries of research, the scientific community eagerly anticipates the applications of his findings.