Fullerton, CA, United States of America

James C Sternberg


Average Co-Inventor Count = 1.7

ph-index = 12

Forward Citations = 656(Granted Patents)


Company Filing History:


Years Active: 1976-1998

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17 patents (USPTO):Explore Patents

Title: Innovations of James C Sternberg

Introduction

James C Sternberg is a notable inventor based in Fullerton, CA (US). He has made significant contributions to the field of biotechnology, particularly in the development of innovative conjugates for immunoassays. With a total of 17 patents to his name, Sternberg's work has had a profound impact on the scientific community.

Latest Patents

One of his latest patents is focused on an analyte assay using a trifunctional conjugate. This trifunctional conjugate features three chemical moieties attached through a spacer moiety. At least two of these chemical moieties are relatively small molecules, typically less than about 7,000 Daltons in size. The spacer moiety is specifically selected to impart certain steric properties to the conjugate. In one embodiment, the binding of a macromolecular specific binding partner to one of the chemical moieties sterically inhibits the binding of a different macromolecule to another chemical moiety. In another embodiment, the binding of a first chemical moiety to a macromolecule restricts the subsequent binding of a second chemical moiety to a proximate location on the same macromolecule. The three chemical moieties are preferably a nitrophenylazido residue, a phenyl boronic acid residue, and a solid support or a label such as biotin. The spacer is preferably cysteine, lysine, glutamic acid, pyroglutamic acid, S-acetylmercaptosuccinic anhydride, or .omega.-carbobenzoxylysine. This conjugate is particularly useful in immunoassays and for targeted labeling of proteins.

Career Highlights

James C Sternberg is currently associated with Beckman Instruments, Inc., where he continues to innovate and develop new technologies. His work has been instrumental in advancing the capabilities of immunoassays, making them more efficient and effective.

Collaborations

Throughout his career, Sternberg has collaborated with notable colleagues, including Fu-Tai A Chen and Chan S Oh. These collaborations have further enriched his research and contributed to the success of his inventions.

Conclusion

James C Sternberg's contributions to the field of biotechnology through his innovative patents and collaborations have established him as a prominent figure in the industry. His work continues to influence the development of advanced

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