Lincoln, NE, United States of America

James Arthur Williams

This inventor holds 54 USPTO granted patents and 13 published patent applications, plus 3 CIPO patents and 12 EPO patents, primarily in Genetic Engineering. Top assignees: Nature Technology Corporation, Ophidian Pharmaceuticals, Inc., Promega Corporation. Active years: 1978-2026.

USPTO Granted Patents = 54 

% Patents Active = 90.7

 

 

Average Co-Inventor Count = 1.3

ph-index = 15

Forward Citations = 570(Granted Patents)

Forward Citations (Not Self Cited) = 553(Dec 10, 2025)


Location History:

  • Sarasota, FL (US) (1978 - 1980)
  • Harvey, LA (US) (1987)
  • Beverly Hills, CA (US) (1993)
  • Studio City, CA (US) (1994)
  • Lansdale, PA (US) (1997)
  • Madison, WI (US) (1997 - 2003)
  • Galion, OH (US) (1999 - 2005)
  • Sulphur, OK (US) (2008)
  • Shelbyville, TN (US) (2006 - 2009)
  • Cypress, TX (US) (2013)
  • Montgomery, TX (US) (2019)
  • Lincoln, NE (US) (2000 - 2023)

Company Filing History:


Years Active: 1978-2026

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Areas of Expertise:
Nanoplasmid Vectors
DNA Vectors
Minicircle Vectors
Genetic Modification
Polypeptide Production
Transgene Silencing
Plasmid Stability
Immunization Methods
C. Difficile Treatment
Vaccine Development
54 patents (USPTO):Explore Patents

Title: Innovations in Genetic Engineering: The Contributions of James Arthur Williams

Introduction

James Arthur Williams, based in Lincoln, NE, is a notable inventor with an impressive portfolio of 34 patents. His groundbreaking work primarily focuses on enhancing the efficiency of genetic engineering through the development of advanced DNA plasmids and replicative minicircle vectors.

Latest Patents

Among his latest patents, Williams has made significant contributions with his inventions targeting DNA plasmids with improved expression. This invention involves the production and utilization of covalently closed circular (ccc) recombinant plasmids that optimize the expression of DNA molecules within target organisms. Furthermore, his work on replicative minicircle vectors with improved expression expands on this concept by addressing the production and application of various recombinant DNA molecules, including plasmids and viral vectors, and enhancing their expression in different cellular contexts.

Career Highlights

Throughout his career, Williams has made impactful changes in the biotechnology field. He has been associated with esteemed institutions like Nature Technology Corporation and Ophidian Pharmaceuticals, Inc., where he contributed his expertise in genetic engineering. His dedication to innovation in the area of biotechnology has not only advanced his own career but has also influenced the field at large.

Collaborations

Collaboration is key in scientific advancements, and Williams has worked alongside notable colleagues such as John A. Kink and Aaron E. Carnes. Together, they have pushed the boundaries of genetic research, fostering an environment of innovation that has led to several successful projects and patents.

Conclusion

James Arthur Williams stands out as a significant figure in the world of genetic engineering and biotechnology. His innovative approaches to DNA plasmids and vector development underscore the importance of continued research and collaboration. As he continues to expand his body of work, his contributions remain invaluable to the scientific community and the advancement of genetic technologies.

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