The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2025
Filed:
Sep. 17, 2018
Applicant:
Deutsches Krebsforschungszentrum, Heidelberg, DE;
Inventors:
James A. Williams, Lincoln, NE (US);
Matthias Bozza, Heidelberg, DE;
Richard Harbottle, Ladenburg, DE;
Assignee:
Deutsches Krebsforschungszentrum, Heidelberg, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); C12N 15/67 (2006.01); C12N 15/79 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); C12N 15/79 (2013.01); C12N 15/67 (2013.01); C12N 2800/106 (2013.01); C12N 2800/108 (2013.01); C12N 2820/55 (2013.01); C12N 2830/46 (2013.01);
Abstract
The present invention relates to a polynucleotide comprising at least one promoter and an S/MAR element, wherein the S/MAR element is located downstream of the promoter in the 3' UTR of the transcription unit and wherein the S/MAR element is flanked by a 5′ splice donor site and a 3′ splice acceptor site; the present invention further relates to a composition comprising the polynucleotide, and to the polynucleotide for use in medicine and for use in treating genetic disease.