logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12215335 B1

PDFFull Text
Date of Patent:
Feb. 04, 2025

Filed:

Sep. 17, 2018

Non-integrating dna vectors for the genetic modification of cells

Applicant:

Deutsches Krebsforschungszentrum, Heidelberg, DE;

Inventors:

James A. Williams, Lincoln, NE (US);

Matthias Bozza, Heidelberg, DE;

Richard Harbottle, Ladenburg, DE;

Assignee:

Deutsches Krebsforschungszentrum, Heidelberg, DE;

Attorney:

Taft Stettinius & Hollister LLP

Primary Examiner:

Joseph G Dauner

Assistant Examiner:

Alexandra Geraldine Dace Denito

Int. Cl.
CPC ...
C12N 15/85 (2006.01); C12N 15/67 (2006.01); C12N 15/79 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); C12N 15/79 (2013.01); C12N 15/67 (2013.01); C12N 2800/106 (2013.01); C12N 2800/108 (2013.01); C12N 2820/55 (2013.01); C12N 2830/46 (2013.01);
Abstract

The present invention relates to a polynucleotide comprising at least one promoter and an S/MAR element, wherein the S/MAR element is located downstream of the promoter in the 3' UTR of the transcription unit and wherein the S/MAR element is flanked by a 5′ splice donor site and a 3′ splice acceptor site; the present invention further relates to a composition comprising the polynucleotide, and to the polynucleotide for use in medicine and for use in treating genetic disease.

Find Patent Forward Citations

Quick Actions:

Williams, James. (2025). Non-integrating dna vectors for the genetic modification of cells (U.S. Patent No. 12215335). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12215335

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…