Company Filing History:
Years Active: 2005-2006
Title: James A. Bradburne: Innovator in Synthetic Proteins
Introduction
James A. Bradburne is a notable inventor based in Redwood City, CA (US). He has made significant contributions to the field of synthetic proteins, holding a total of 3 patents. His work focuses on enhancing the biological activity and pharmacokinetic properties of proteins through innovative methods.
Latest Patents
One of his latest patents is related to polymer-modified synthetic proteins. This invention involves methods and compositions for modifying peptides, polypeptides, and proteins with polymers, particularly glyco-mimetic polymers. The goal is to improve their biological activity or pharmacokinetic properties. The invention also provides methods and uses for such polymer-modified peptides, polypeptides, and proteins, making it particularly suitable for synthesizing polymer-modified synthetic bioactive proteins and pharmaceutical compositions containing these proteins.
Another significant patent by Bradburne is the pseudo native chemical ligation. This invention extends the technique of native chemical ligation to a wider range of peptides, polypeptides, and other molecules via an amide bond. It also provides methods and uses for such proteins and derivatized proteins, making it particularly useful in synthesizing optionally polymer-modified, synthetic bioactive proteins and pharmaceutical compositions that include these proteins.
Career Highlights
Throughout his career, James A. Bradburne has worked with prominent companies in the biotechnology sector, including Gryphon Therapeutics, Inc. and Amylin Pharmaceuticals, Inc. His expertise in synthetic proteins has positioned him as a valuable asset in these organizations.
Collaborations
Bradburne has collaborated with notable professionals in his field, including Paolo Botti and Stephen B. H. Kent. These collaborations have further enriched his work and contributed to advancements in synthetic protein technologies.
Conclusion
James A. Bradburne is a distinguished inventor whose work in synthetic proteins has led to significant advancements in the field. His innovative patents and collaborations highlight his commitment to improving biological activity and pharmacokinetic properties of proteins.
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