The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2006
Filed:
Jul. 12, 2001
Gerd G. Kochendoerfer, Oakland, CA (US);
Paolo Botti, Piacenza, IT;
James A. Bradburne, Redwood City, CA (US);
Shiah-yun Chen, Mountain View, CA (US);
Sonya Cressman, Ladysmith, CA;
Christie L. Hunter, San Mateo, CA (US);
Stephen B. H. Kent, San Francisco, CA (US);
Donald W. Low, Burlingame, CA (US);
Jill G. Wilken, Walnut Creek, CA (US);
Gerd G. Kochendoerfer, Oakland, CA (US);
Paolo Botti, Piacenza, IT;
James A. Bradburne, Redwood City, CA (US);
Shiah-yun Chen, Mountain View, CA (US);
Sonya Cressman, Ladysmith, CA;
Christie L. Hunter, San Mateo, CA (US);
Stephen B. H. Kent, San Francisco, CA (US);
Donald W. Low, Burlingame, CA (US);
Jill G. Wilken, Walnut Creek, CA (US);
Amylin Pharmaceuticals, Inc., San Diego, CA (US);
Abstract
The present invention relates to methods and compositions for modifying peptides, polypeptides and proteins with polymers, especially glyco-mimetic polymers, so as to improve their biological activity or pharmacokinetic properties. The invention further provides methods and uses for such polymer-modified peptides, polypeptides and proteins. The invention is particularly suitable for use in the synthesis of polymer-modified synthetic bioactive proteins (FIG.D), and of pharmaceutical compositions that contain such proteins.