The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2006
Filed:
Jul. 12, 2001
Christie L. Hunter, San Mateo, CA (US);
Paolo Botti, Piacenza, IT;
James A. Bradburne, Redwood City, CA (US);
Shiah-yun Chen, Mountain View, CA (US);
Sonya Cressman, Ladysmith, CA;
Stephen B. H. Kent, San Francisco, CA (US);
Gerd G. Kochendoerfer, Oakland, CA (US);
Donald W. Low, Burlingame, CA (US);
Christie L. Hunter, San Mateo, CA (US);
Paolo Botti, Piacenza, IT;
James A. Bradburne, Redwood City, CA (US);
Shiah-yun Chen, Mountain View, CA (US);
Sonya Cressman, Ladysmith, CA;
Stephen B. H. Kent, San Francisco, CA (US);
Gerd G. Kochendoerfer, Oakland, CA (US);
Donald W. Low, Burlingame, CA (US);
Gryphon Therapeutics, South San Francisco, CA (US);
Abstract
The present invention concerns methods and compositions for extending the technique of native chemical ligation of a wider range of peptides, polypeptides, other polymers and other molecules via an amide bond (see FIG.). The invention further provides methods and uses for such proteins and derivatized proteins. The invention is particularly suitable for use in the synthesis of optionally polymer-modified, synthetic bioactive proteins, and of pharmaceutical compositions that contain such proteins.