Jae Ick Sim

Title: Jae Ick Sim: Innovator in Biochemical Engineering

Introduction

Jae Ick Sim is a notable inventor based in Icheon-si, South Korea. He has made significant contributions to the field of biochemical engineering, particularly in the development of innovative enzymatic processes. With a total of two patents to his name, his work has implications for industrial applications.

Latest Patents

One of Jae Ick Sim's latest patents is focused on ammonia-specific 5'-XMP aminase mutants. This invention discloses a method for preparing these mutants, which involve introducing a mutation into the active site of glutamine-dependent catalysis in 5'-XMP aminase. The resulting mutant is devoid of glutamine-dependent activity and specifically reacts with external ammonia to convert 5'-XMP into 5'-GMP. This ammonia-specific 5'-XMP aminase mutant demonstrates greater stability within cells compared to the wild type and holds potential for industrial conversion processes. Another patent involves a microorganism of a specific genus that produces inosine while blocking the inosine catabolic pathway. This microorganism exhibits a leaky adenine auxotrophic phenotype and a leaky guanine auxotrophic phenotype, along with a method for producing inosine through culturing.

Career Highlights

Jae Ick Sim is currently employed at CJ Cheiljedang Corporation, where he continues to advance his research and development efforts. His work at the company has allowed him to explore innovative solutions in the biochemical sector.

Collaborations

Throughout his career, Jae Ick Sim has collaborated with notable colleagues, including Jeong Hwan Kim and Jae-Gu Pan. These collaborations have contributed to the advancement of his research and the successful development of his patents.

Conclusion

Jae Ick Sim is a distinguished inventor whose work in biochemical engineering has led to significant advancements in enzymatic processes. His innovative patents reflect his commitment to enhancing industrial applications in the field.