The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 2014
Filed:
Dec. 14, 2006
Jae-gu Pan, Chungeheongnam-do, KR;
Heung-chae Jung, Daejeon, KR;
Eui-joong Kim, Daejeon, KR;
Han-seung Lee, Daejeon, KR;
Young Hoon Park, Gyeonggi-do, KR;
Hyoung Suk Kim, Gyeonggi-do, KR;
Jong-kwon Han, Gyeonggi-do, KR;
Jin Nam Lee, Gyeonggi-do, KR;
Ki-hoon OH, Seoul, KR;
Jeong Hwan Kim, Seoul, KR;
Yoon-suk OH, Gyeonggi-do, KR;
Jae Ick Sim, Gyeonggi-do, KR;
Kuk-ki Hong, Seoul, KR;
Kyung OH Choi, Busan, KR;
Hyun Soo Kim, Gyeonggi-do, KR;
Min-ji Baek, Seoul, KR;
Tae Sun Kang, Seoul, KR;
Jae-Gu Pan, Chungeheongnam-do, KR;
Heung-Chae Jung, Daejeon, KR;
Eui-Joong Kim, Daejeon, KR;
Han-Seung Lee, Daejeon, KR;
Young Hoon Park, Gyeonggi-do, KR;
Hyoung Suk Kim, Gyeonggi-do, KR;
Jong-Kwon Han, Gyeonggi-do, KR;
Jin Nam Lee, Gyeonggi-do, KR;
Ki-Hoon Oh, Seoul, KR;
Jeong Hwan Kim, Seoul, KR;
Yoon-Suk Oh, Gyeonggi-do, KR;
Jae Ick Sim, Gyeonggi-do, KR;
Kuk-Ki Hong, Seoul, KR;
Kyung Oh Choi, Busan, KR;
Hyun Soo Kim, Gyeonggi-do, KR;
Min-Ji Baek, Seoul, KR;
Tae Sun Kang, Seoul, KR;
CJ Cheiljedang Corporation, Seoul, KR;
Abstract
Disclosed herein are ammonia-specific 5'-XMP aminase mutants and a method for preparing the same. A mutation is introduced into the active site of glutamine-dependent catalysis in 5′-XMP aminase. The resulting 5′-XMP aminase mutant is devoid of the glutamine-dependent activity and specifically reacts with external ammonia in converting 5′-XMP into 5′-GMP. Thus, the ammonia-specific 5′-XMP aminase mutant is stabler within cells compared to the wild type, and can be useful in the industrial conversion of 5′-XMP into 5′-GMP.