Jack C Rife

Title: Jack C Rife - Innovator in Biochemical Assays

Introduction

Jack C Rife is a distinguished inventor based in Washington, DC, known for his significant contributions to the field of biochemical assays. He holds a total of 7 patents, showcasing his innovative approach to enhancing the performance of various scientific methods.

Latest Patents

One of his latest patents, titled "Fluidic Force Discrimination," describes a method of using controlled fluidic forces to improve the performance of a biochemical binding assay. In this invention, a target molecule is captured by specific molecular recognition onto a substrate surface with an affinity coating. The target is then labeled with a detectable micrometer-scale particle through a second specific molecular recognition reaction. By utilizing specific ranges of label sizes and laminar flow conditions, controlled fluidic forces can be applied to the label particles. This allows for the selective removal of molecules bound to a surface based on their binding strength, ultimately increasing the ratio of specifically bound labels to more weakly attached non-specifically bound labels. This method can be applied to a wide variety of label types and associated detection methods, thereby improving the sensitivity and selectivity of a broad range of binding assays.

Career Highlights

Throughout his career, Jack has worked with notable organizations, including the United States of America, as represented by the Secretary of the Navy, and Baker Manufacturing Company, Inc. His work has significantly impacted the field of biochemical research