Skillman, NJ, United States of America

J Craig Franklin


Average Co-Inventor Count = 5.6

ph-index = 6

Forward Citations = 188(Granted Patents)


Location History:

  • East Windsor, NJ (US) (1999 - 2000)
  • Princeton, NJ (US) (1996 - 2001)
  • Skillman, NJ (US) (2000 - 2002)

Company Filing History:


Years Active: 1996-2002

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13 patents (USPTO):Explore Patents

Title: J Craig Franklin: Innovator in Taxane Therapeutics

Introduction

J Craig Franklin is a notable inventor based in Skillman, NJ (US), recognized for his contributions to the field of pharmaceuticals, particularly in the development of taxane derivatives. With a total of 13 patents to his name, Franklin has made significant strides in enhancing therapeutic activities for cancer and inflammatory diseases.

Latest Patents

One of Franklin's latest patents focuses on hydrolysis-promoting hydrophobic taxane derivatives. This innovation involves a taxane that has a hydrocarbon attached at the 2′ and/or 7 positions, with the hydrocarbon's alpha position occupied by a hydrolysis-promoting group (HPG). The stereospecific attachment of the HPG to the alpha-carbon of the hydrophobic taxane allows for enhanced in vivo hydrolysis of the hydrocarbon-taxane bond. This substitution leads to improved taxane therapeutic activity, making it a valuable advancement in cancer treatment. Additionally, the patent includes taxane-containing compositions and methods for administering these compounds to animals suffering from various ailments.

Career Highlights

Throughout his career, J Craig Franklin has worked with prominent companies in the pharmaceutical industry, including The Liposome Company, Inc. and Elan Pharmaceutical Technologies, Inc. His work has significantly impacted the development of innovative therapeutic solutions.

Collaborations

Franklin has collaborated with esteemed colleagues such as Andrew S Janoff and Eric G Mayhew, contributing to the advancement of research and development in his field.

Conclusion

J Craig Franklin's innovative work in taxane therapeutics exemplifies the importance of research and development in the pharmaceutical industry. His patents and collaborations continue to pave the way for advancements in cancer treatment and therapeutic efficacy.

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