The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 15, 2002
Filed:
Jun. 29, 1999
Paul R. Meers, Princeton, NJ (US);
Charles Pak, Princeton, NJ (US);
Shaukat Ali, Monmouth Junction, NJ (US);
Andrew Janoff, Yardley, PA (US);
J. Craig Franklin, Skillman, NJ (US);
Ravi K. Erukulla, Plainsboro, NJ (US);
Donna Cabral-Lilly, Princeton, NJ (US);
Patrick L. Ahl, Princeton, NJ (US);
Elan PharmaceuticalsTechnologies, Inc., King of Prussia, PA (US);
Abstract
Peptide-lipid conjugates are incorporated into liposomes so as to selectively destabilize the liposomes in the vicinity of target peptidase-secreting cells, and hence, to deliver the liposomes to the vicinity of the target cells, or directly into the cells. The liposomes can thus be used to treat mammals for diseases, disorders or conditions, e.g., tumors, microbial infection and inflammations, characterized by the occurrence of peptidase-secreting cells.