Cambridge, MA, United States of America

Isabel Kalofonos

USPTO Granted Patents = 6 

 

 

Average Co-Inventor Count = 5.1

ph-index = 1

Forward Citations = 3(Granted Patents)


Company Filing History:


Years Active: 2014-2019

where 'Filed Patents' based on already Granted Patents

6 patents (USPTO):

Title: Isabel Kalofonos: Innovator in Pharmaceutical Chemistry

Introduction

Isabel Kalofonos is a distinguished inventor based in Cambridge, MA (US), known for her significant contributions to pharmaceutical chemistry. With a total of six patents to her name, she has made remarkable strides in the development of novel therapeutic compounds.

Latest Patents

One of her latest patents is the choline cocrystal of epalrestat. This invention relates to a novel choline cocrystal of 5-[(1Z,2E)-2-methyl-3-phenylpropenylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid. The preparation and characterization of this novel choline cocrystal are described in detail. The invention also encompasses pharmaceutical compositions containing the choline cocrystal and its therapeutic applications. These applications include treating and preventing various conditions such as diabetic complications, homocystinuria, and reducing levels of homocysteine in blood serum. Additionally, it aims to inhibit aldose reductase and provide cardioprotection in non-diabetic patients.

Career Highlights

Isabel has worked with notable companies in the pharmaceutical sector, including Bionevia Pharmaceuticals, Inc. and Bionevia, LLC. Her work has significantly impacted the field, particularly in the development of innovative treatments.

Collaborations

Throughout her career, Isabel has collaborated with esteemed colleagues such as William Martin-Doyle and G. Patrick Stahly. These partnerships have further enhanced her research and contributions to the industry.

Conclusion

Isabel Kalofonos stands out as a prominent inventor in pharmaceutical chemistry, with her innovative work paving the way for advancements in treatment options. Her dedication to research and collaboration continues to influence the field positively.

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