Location History:
- Tutzing, DE (1996)
- Bernried, DE (1999 - 2001)
- Mannheim, DE (2007)
Company Filing History:
3 out of 1,164 
1 out of 15,475 
1 out of 480 
Years Active: 1996-2007
Title: **Ilse Bartke: Pioneer in Neurobiology and Nerve Growth Factor Innovations**
Introduction
Ilse Bartke is a distinguished inventor based in Bernried, Germany, who has made significant contributions to the field of neurobiology. With a total of five patents to her name, Bartke has focused on the prevention of demyelination in the nervous system, particularly in relation to diseases such as multiple sclerosis. Her innovative research is centered around the therapeutic potential of nerve growth factors.
Latest Patents
One of Bartke's latest patents addresses the use of nerve growth factor (NGF) for preventing demyelination in the nervous system. This groundbreaking invention highlights NGF's capability to inhibit the further demyelination of nervous tissue in conditions characterized by inflammation. The proposed method involves administering an effective amount of NGF or its analogues to decrease the activity of T cells in the central nervous system while promoting the production of IL-10 by glial cells.
Another notable patent by Bartke presents a method for the in vivo regeneration of oligodendrocytes through bolus injection of human β nerve growth factor (NGF-β). This treatment aims to assist patients with demyelination diseases, allowing for the regeneration of essential oligodendrocytes. The protocol involves administering 1-10 bolus injections in specific dosages over a period of 1 to 21 days.
Career Highlights
Throughout her career, Ilse Bartke has been associated with reputable organizations such as Boehringer Mannheim GmbH and the University of California. Her role in these institutions has allowed her to advance her research and collaborate with prominent experts in the field of neurobiology.
Collaborations
Bartke has worked alongside notable colleagues like Kurt W. Naujoks and Jurgen Unger. These collaborations have enriched her innovative projects and facilitated the advancement of her research into nerve growth factors and their applications in treating neurological disorders.
Conclusion
Ilse Bartke's work stands at the forefront of neurobiological innovations addressing demyelination in the nervous system. Her commitment to researching nerve growth factors underscores the critical need for effective therapies in treating inflammatory diseases such as multiple sclerosis. Bartke's contributions continue to inspire advancements in medical science and have the potential to enhance the lives of countless individuals affected by neurological conditions.