The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 23, 1999
Filed:
Feb. 28, 1995
Applicant:
Inventors:
Assignees:
Boehringer Mannheim GmbH, Manheim, DE;
Max-Planck-Gesellschaft zur Forderung der Wissenschaften, E.V., Gottingen, DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ;
U.S. Cl.
CPC ...
4241981 ; 514 12 ; 514 21 ; 530350 ;
Abstract
The invention concerns a process for improving the regeneration of oligodendrocytes, in particular of human oligodendrocytes, in which oligodendrocytes are treated in cell culture with nerve growth factor (NGF) or active fragments of NGF. Furthermore a composition is disclosed for treating diseases in which a demyelination of nerve fibres occurs which contains NGF or an active fragment thereof as the active substance, if desired, together with the usual pharmaceutical vehicles, auxiliary substances, fillers and diluents.