Company Filing History:
Years Active: 2019-2024
Title: Innovations of Hyunsung John Kim
Introduction
Hyunsung John Kim is a prominent inventor based in San Francisco, CA. He has made significant contributions to the field of molecular biology and genomics, holding a total of 4 patents. His work focuses on advancing methods for analyzing cell-free nucleic acids, which has important implications for diagnostics and personalized medicine.
Latest Patents
One of his latest patents is titled "Methods of preparing and analyzing cell-free nucleic acid sequencing libraries." This invention relates to methods for preparing and analyzing a sequencing library from a mixed cell-free DNA (cfDNA) sample. The mixed sample includes double-stranded DNA (dsDNA), damaged dsDNA, and single-stranded DNA (ssDNA) molecules. The methods facilitate the collection of information from these various DNA types, providing enhanced diagnostic information compared to sequencing libraries prepared from dsDNA alone.
Another notable patent is "Alignment free filtering for identifying fusions." In this invention, cell-free nucleic acids from a test sample are analyzed to identify possible fusion events. The nucleic acids are sequenced and processed to generate fragments, which are then decomposed into kmers. These kmers can be analyzed de novo or compared to targeted nucleic acid sequences associated with fusion gene pairs of interest. This innovative approach allows for the identification of kmers that may have originated from fusion events, thereby enhancing the understanding of genetic alterations.
Career Highlights
Hyunsung John Kim is currently employed at Grail, Inc., a company dedicated to early cancer detection through innovative genomic technologies. His work at Grail has positioned him as a key player in the development of advanced diagnostic tools that leverage the power of cell-free nucleic acid analysis.
Collaborations
He collaborates with talented individuals such as Xiao Yang and Matthew H Larson, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Hyunsung John Kim's contributions to the field of molecular biology through his patents and work at Grail, Inc. highlight his role as a leading inventor in the realm of genomic analysis. His innovative methods are paving the way for improved diagnostic capabilities in healthcare.