Hua Zhang

Title: Innovations and Contributions of Inventor Hua Zhang

Introduction

Hua Zhang is a prominent inventor based in Houston, TX (US), known for his significant contributions to the field of biomedical engineering and power transfer systems. With a total of 8 patents, his work focuses on developing innovative solutions for critical health issues and enhancing power transfer technologies.

Latest Patents

One of Zhang's latest patents involves Rho associated kinase (ROCK) inhibitors and their application in treating various diseases. This patent describes peptide inhibitors that target ROCK, which is crucial in managing disorders such as heart failure, a leading cause of morbidity and mortality in the United States. The invention includes an inhibitory polypeptide that effectively blocks ROCK1 activity in the presence of 1 mM ATP. The binding epitope on ROCK1 was identified using chemical cross-linking, revealing a novel locus that could lead to a new class of inhibitory drugs. These peptides have the potential to address several significant health challenges, including heart disease, pulmonary hypertension, and acute myeloid leukemia.

Another notable patent by Zhang is the development of a double-sided LCLC-compensated topology for capacitive power transfer (CPT) systems. This innovative design utilizes four metal plates to create two power transmitting and receiving capacitors, with an LCLC network compensating the capacitors. The design also includes a CLLC topology variation. A prototype capable of transferring 3.1 kW output power through a 70 mm air gap was successfully built, achieving a remarkable dc-to-dc efficiency of 92.1%.

Career Highlights

Hua Zhang has worked at prestigious institutions such as the University of Michigan and the University of Houston System. His research and inventions have significantly impacted both academic and practical applications in his fields of expertise.

Collaborations

Zhang has collaborated with notable colleagues, including Xiaolian Gao and Eric M Leproust, contributing to the advancement of innovative technologies and research.

Conclusion

Hua Zhang's work exemplifies the spirit of innovation and dedication to improving health and technology. His patents and research continue to pave the way for advancements in medical treatments and power transfer systems.