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Howard Chou

This inventor holds 22 USPTO granted patents and 2 published patent applications and 6 EPO patents. Top assignees: Cibt America Inc., Cathay Biotech Inc., Cathay Biotec Inc.. Active years: 2019-2025.

USPTO Granted Patents = 22 (Patent Applications = 2)

% Patents Active = 100.0

EPO Patents = 6 (Patent Applications = 18)

Average Co-Inventor Count = 3.3

ph-index = 1

Forward Citations = 6(Granted Patents)

Company Filing History:

Cathay R&d Center Co., Ltd

patents

where one patent can have more than one assignee

Years Active: 2019-2025

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22 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12325872 - Method of improving acid decarboxylase activity in vitro under alkaline pH (2025-06-10),

2. 12018311 - Long chain dibasic acid with low content of long chain dibasic acid impurity of shorter carbon-chain and preparation method thereof (2024-06-25),

3. 11781163 - Reducing the accumulation of imines/enamines for the production of amino acids or amino acid-derived products (2023-10-10),

4. 11753629 - Directed evolution of CYP52A12 gene and its use in dicarboxylic acid production (2023-09-12),

5. 11512302 - Modifications to lysine decarboxylase enzymes (2022-11-29),

6. 11485986 - Cells and methods for production of lysine and lysine-derived products (2022-11-01),

7. 11434510 - Long chain dibasic acid with low content of long chain dibasic acid impurity of shorter carbon-chain and preparation method thereof (2022-09-06),

8. 11261217 - Expression ofpolypeptides involved in lysine decarboxylation, and methods and applications thereof (2022-03-01),

9. 11225677 - Long-chain dibasic acid with low content of monobasic acid impurity and the production method thereof (2022-01-18),

10. 11155840 - Heterologous expression of thermophilic lysine decarboxylase and uses thereof (2021-10-26),

11. 11136596 - Long-chain dibasic acid with low content of hydroxyl acid impurity and production method thereof (2021-10-05),

12. 11118201 - Heterologous expression of carbohydrate binding modules and uses thereof for cadaverine production (2021-09-14),

13. 11098329 - Expression of recombinant tetracycline efflux pumps for the production of lysine or lysine-derived products, and methods and applications thereof (2021-08-24),

14. 11091742 - Directed evolution of CYP52A12 gene and its use in dicarboxylic acid production (2021-08-17),

15. 11078473 - Lysine decarboxylases having modifications at titratable amino acids (2021-08-03),

Title: Profile of Howard Chou: Innovator in Biochemical Advancements

Introduction: Howard Chou is a prominent inventor based in Shanghai, China, known for his innovative contributions in the field of biotechnology. With a remarkable portfolio of 21 patents, he has made significant strides in developing processes and microorganisms that enhance the production of valuable biochemical compounds.

Latest Patents: Among his notable inventions is a long-chain dibasic acid characterized by a low content of impurities from shorter carbon-chain dibasic acids. This invention includes a method for preparing a strain through directed evolution of the POX gene and homologous recombination, ultimately leading to a fermentation process that significantly reduces undesirable impurities. Another significant patent focuses on genetically modified microorganisms that overexpress an imine/enamine deaminase, enhancing lysine production and its derivatives. This innovation provides a pathway for creating microorganisms that boost the efficiency of amino acid and amino acid-derived product manufacturing.

Career Highlights: Howard Chou has held influential positions within companies such as Cibt America Inc. and Cathay Biotech Inc. His work in these organizations has propelled advancements in the biotechnology sector, positioning him as a leader in his field.

Collaborations: Throughout his career, Howard has collaborated with esteemed colleagues, including Xiucai Liu and Wenbo Liu. These partnerships have fostered a collaborative spirit that drives innovation and enhances research outcomes.

Conclusion: With a diverse array of patents and contributions to biotechnology, Howard Chou exemplifies the spirit of innovation. His work not only addresses current challenges in biochemical production but also paves the way for future advancements in the field.

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