The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2021
Filed:
Dec. 30, 2016
Applicants:
Cathay Biotech Inc., Shanghai, CN;
Cibt America Inc., Newark, DE (US);
Inventors:
Howard Chou, Shanghai, CN;
Ling Chen, Shanghai, CN;
Wenqiang Lu, Shanghai, CN;
Xiucai Liu, Shanghai, CN;
Assignees:
CATHAY BIOTECH INC., Shanghai, CN;
CIBT AMERICA INC., Newark, DE (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/88 (2006.01); C12P 13/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/88 (2013.01); C12P 13/001 (2013.01); C12Y 401/01018 (2013.01);
Abstract
The invention provides CadA polypeptides with mutations that increase activity in alkaline pH compared to the wild-type lysine decarboxylase. The invention also provides methods of generating such mutant polypeptides, microorganisms genetically modified to overexpress the mutant polypeptides, and methods of generating such microorganisms.