Company Filing History:
Years Active: 2019-2020
Title: Innovations of Hongyan Han in Nucleic Acid Fragmentation
Introduction
Hongyan Han is a notable inventor based in Shenzhen, China. He has made significant contributions to the field of nucleic acid research, particularly in the area of random fragmentation methods. With a total of two patents to his name, Han's work is paving the way for advancements in genetic analysis and biotechnology.
Latest Patents
Hongyan Han's latest patents include a primer for nucleic acid random fragmentation and a nucleic acid random fragmentation method. The primer consists of a plurality of upstream random primers and downstream random primers. The sequence composition of the upstream random primers is 5'-X-Y-3', and the sequence composition of the downstream random primers is 5'-P-Y'-X'-close-3', wherein Y and Y' are random sequences, X is all or part of sequences of a sequencing platform 5' end adaptor, X' is all or part of sequences of a sequencing platform 3' end adaptor, P is phosphorylation modification, and close is close modification. This innovative primer adopts double random anchoring of both the upstream and downstream random primers, allowing for random fragmentation of DNA samples. Additionally, his method for nucleic acid fragmentation involves subjecting a denatured nucleic acid to annealing and an extension reaction using a single-stranded 5'-end extension primer. This method results in a fragmented single-stranded nucleic acid with adaptor sequences on both ends.
Career Highlights
Hongyan Han is currently employed at MGI Tech Co., Ltd., where he continues to develop his innovative ideas. His work is instrumental in enhancing the capabilities of nucleic acid analysis, which is crucial for various applications in genomics and molecular biology.
Collaborations
Some of his coworkers include Chunyu Geng and Wenwei Zhang, who contribute to the collaborative environment at MGI Tech Co., Ltd. Their combined efforts are essential in driving forward the research and development initiatives within the company.
Conclusion
Hongyan Han's contributions to nucleic acid fragmentation represent a significant advancement in biotechnology. His innovative patents and ongoing work at MGI Tech Co., Ltd. highlight his role as a leading inventor in this critical field.
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