Hongli Guo

Title: **Innovations of Hongli Guo: Pioneering Advances in Pharmaceutical and Petrochemical Patents**

Introduction

Hongli Guo, an accomplished inventor based in Shanghai, China, has made significant contributions to the fields of pharmaceuticals and petrochemicals. With a remarkable portfolio of four patents, Guo is recognized for his innovative approaches that address critical challenges in medicine and chemical production.

Latest Patents

Among Hongli Guo's latest patents is the development of a **cyclic dinucleotide analogue**, which offers a pharmaceutical composition and its applications. This cyclic dinucleotide analogue, along with its isomers, prodrugs, stable isotope derivatives, and pharmaceutically acceptable salts, is designed to act as a regulator of the stimulator of interferon genes (STING) pathway. It has demonstrated effectiveness in treating and relieving various conditions, including malignant tumors, inflammations, autoimmune diseases, and infectious diseases. Notably, the STING regulator can also serve as a vaccine adjuvant, highlighting its potential for enhancing immune responses.

Another significant patent from Guo is an **integrated process for the production of p-xylene**. This innovative process involves processing a mixed feedstock that includes benzene, toluene, and other hydrocarbons through various operations and units. The method encompasses a dealkylation unit, a toluene selective disproportionate unit, an adsorption separation unit, an isomerization unit, and a crystallization separation unit, ultimately optimizing the production of p-xylene.

Career Highlights

Hongli Guo has worked with prominent organizations such as the China Petroleum & Chemical Corporation (Sinopec) and the Shanghai Research Institute of Petrochemical Technology. His professional journey has been characterized by a focus on enhancing production methods and developing advanced pharmaceutical compounds, illustrating his dedication to innovation.

Collaborations

Throughout his career, Guo has collaborated with talented professionals, including his coworkers Dejin Kong and Weisheng Yang. These partnerships reflect his commitment to teamwork and knowledge sharing in the pursuit of groundbreaking inventions.

Conclusion

In summary, Hongli Guo stands out as a distinguished inventor whose work spans critical advancements in both pharmaceuticals and petrochemicals. His recent patents not only contribute to addressing significant health challenges but also enhance production efficiencies within the chemical industry. With his innovative spirit and collaborative efforts, Guo continues to pave the way for future breakthroughs in these vital fields.