The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2024

Filed:

Sep. 18, 2019
Applicant:

Shanghai DE Novo Pharmatech Co., Ltd., Shanghai, CN;

Inventors:

Zhaolong Tong, Shanghai, CN;

Ping Qin, Shanghai, CN;

Fengtao Liu, Shanghai, CN;

Jinglu Wang, Shanghai, CN;

Xiaolei Deng, Shanghai, CN;

Hongli Guo, Shanghai, CN;

Dawei Chen, Shanghai, CN;

Daxin Gao, Shanghai, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07H 21/02 (2013.01); A61K 39/0011 (2013.01); A61K 45/06 (2013.01); A61K 2039/5152 (2013.01);
Abstract

A cyclic dinucleotide analogue, a pharmaceutical composition thereof, and application. A cyclic dinucleotide analogue (I), an isomer thereof, a prodrug, a stable isotope derivative, or a pharmaceutically acceptable salt has the following structure. The cyclic dinucleotide analogue can be used as a regulator of a stimulator of interferon genes (STING) and a related signal path thereof, and can effectively treat and/or relieve multiple types of diseases, including but not limited to malignant tumors, inflammations, autoimmune diseases, and infectious diseases. In addition, the STING regulator can also be used as a vaccine adjuvant.


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