Company Filing History:
Years Active: 2017-2020
Title: Innovations of Inventor Hongkai Zhang
Introduction
Hongkai Zhang is a prominent inventor based in San Diego, CA. He has made significant contributions to the field of biochemistry and pharmacology, holding a total of 4 patents. His work primarily focuses on developing methods and compositions that target G protein-coupled receptors (GPCRs), which play a crucial role in various physiological processes.
Latest Patents
One of his latest patents is titled "Methods and compositions related to GPCR agonist polypeptides." This invention provides combinatorial peptide or polypeptide libraries that can become membrane tethered once expressed in cells. The invention also offers methods for selecting peptide modulators, such as agonists of GPCRs from these combinatorial libraries. Additionally, it introduces novel GPCR polypeptide modulators, including biased polypeptide agonists of the glucagon-like peptide 1 receptor (GLP-1R). The invention further outlines methods for promoting insulin sensitivity, lowering blood glucose, and reducing body weight, as well as methods for treating diseases such as diabetes and obesity.
Another significant patent is "Proximity based methods for selection of binding partners." This invention provides methods for identifying binding partners, such as peptide ligands, that bind to a target protein, like a cellular receptor. The methods involve co-localized expression of the target protein and candidate binding partners, allowing for the selection of binding partners based on their proximity in the plasma membrane.
Career Highlights
Hongkai Zhang is affiliated with The Scripps Research Institute, where he continues to advance his research and innovations. His work has garnered attention for its potential applications in treating metabolic disorders and enhancing drug discovery processes.
Collaborations
He has collaborated with notable colleagues, including Richard A. Lerner and Jia Xie, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Hongkai Zhang's contributions to the field of biochemistry through his innovative patents highlight his role as a leading inventor. His work not only advances scientific understanding but also holds promise for developing new therapeutic strategies.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.