The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2020
Filed:
Oct. 16, 2015
Applicant:
The Scripps Research Institute, La Jolla, CA (US);
Inventors:
Richard A. Lerner, La Jolla, CA (US);
Hongkai Zhang, San Diego, CA (US);
Jia Xie, San Diego, CA (US);
Assignee:
The Scripps Research Institute, La Jolla, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/10 (2006.01); G01N 33/566 (2006.01); G01N 33/542 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1037 (2013.01); C12N 15/1055 (2013.01); C12N 15/1086 (2013.01); G01N 33/542 (2013.01); G01N 33/566 (2013.01); G01N 2333/726 (2013.01);
Abstract
The invention provides methods for identifying binding partners (e.g., peptide ligands) that binds to a target protein (e.g., a cellular receptor). The methods entail co-localized expression of the target protein and candidate binding partners, and selection of binding partners based on their proximity in the plasma membrane.