Hong Yang

Title: Innovations of Hong Yang in Biocatalysis

Introduction

Hong Yang is a notable inventor based in Singapore, recognized for his contributions to the field of biocatalysis. He holds three patents, showcasing his innovative approach to antibiotic synthesis. His work primarily focuses on engineered biocatalysts that enhance the production of essential pharmaceuticals.

Latest Patents

One of Hong Yang's significant patents is related to engineered pNB esterase polypeptides that are useful for the synthesis of the carbapenem antibiotic, imipenem. This patent provides detailed information on polynucleotides encoding the engineered pNB esterases, host cells capable of expressing these enzymes, and methods for utilizing them in the production of imipenem. This innovation is crucial for improving the efficiency of antibiotic synthesis.

Career Highlights

Throughout his career, Hong Yang has worked with prominent companies such as Codexis, Inc. and Globalfoundries Singapore Pte. Ltd. His experience in these organizations has allowed him to develop and refine his expertise in biocatalysis and pharmaceutical production.

Collaborations

Hong Yang has collaborated with notable colleagues, including Joly Sukumaran and Derek J Smith. These partnerships have contributed to his innovative research and development efforts in the field.

Conclusion

Hong Yang's work in engineered biocatalysts represents a significant advancement in antibiotic synthesis. His patents and collaborations highlight his commitment to innovation in the pharmaceutical industry.