Company Filing History:
Years Active: 2017-2023
Title: Hiroki Torikai: Innovator in Immunotherapy
Introduction
Hiroki Torikai is a prominent inventor based in Houston, TX (US), known for his significant contributions to the field of immunotherapy. With a total of 4 patents, he has made remarkable advancements in the application of engineered chimeric antigen receptor (CAR) T-cells for treating various diseases, including cancer.
Latest Patents
One of his latest patents focuses on the human application of engineered chimeric antigen receptor (CAR) T-cells. This invention concerns methods and compositions for immunotherapy that employ a modified T cell comprising a chimeric antigen receptor (CAR). In particular aspects, CAR-expressing T-cells are produced using electroporation in conjunction with a transposon-based integration system. This innovative approach allows for the generation of CAR-expressing cells that require minimal ex vivo expansion or can be directly administered to patients for disease treatment. Another notable patent involves CAR+ T cells that are genetically modified to eliminate the expression of T-cell receptor and/or HLA. This invention also concerns methods and compositions for immunotherapy employing a modified T cell with disrupted T cell receptor and/or HLA, which can be used allogeneically as universal reagents for 'off-the-shelf' treatment of medical conditions such as cancer, autoimmunity, and infection.
Career Highlights
Hiroki Torikai has worked with esteemed organizations, including the University of Texas System and Sangamo Therapeutics, Inc. His work in these institutions has allowed him to further his research and development in the field of immunotherapy, contributing to the advancement of medical treatments.
Collaborations
Throughout his career, Hiroki has collaborated with notable colleagues, including Ling Zhang and Helen Huls. These partnerships have played a crucial role in enhancing his research and expanding the impact of his inventions.
Conclusion
Hiroki Torikai's innovative work in the field of immunotherapy, particularly with CAR T-cells, showcases his dedication to advancing medical science. His contributions are paving the way for new treatment options for patients suffering from various diseases.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.