Herman H Grootveld

Title: The Innovative Journey of Herman H Grootveld

Introduction

Herman H Grootveld is a prominent inventor based in Benthuizen, Netherlands. He has made significant contributions to the field of pharmaceuticals, particularly with his expertise in cephalosporin compounds. With a total of five patents to his name, Grootveld's work has impacted the development of medicinal chemistry.

Latest Patents

Herman H Grootveld's latest patents highlight his innovative approach in the area of cephalosporin derivatives. His first notable patent involves "Cephem derivatives," a cephalosporin compound substituted in the 7-position with a (cyclo)alkylideneammonio group. The formula is defined such that X' represents an anion from an acid HX, while R1 and R2 are individual C1-C16 alkyl groups, or together they can form a cycloalkylidene ring containing up to 8 carbon atoms. This compound serves as a useful intermediate in medicinal applications.

Additionally, Grootveld's patent on "Cephalosporin derivatives" introduces a process for the preparation of 7β-amino-3-substituted methyl-3-cephem-4-carboxylic acid derivatives. This includes new intermediates comprising 7β-(cyclo)alkylideneammonio-3-halomethyl-3-cephem-4-carboxylic acid derivatives, along with 7β-amino/ammonio-3-bromomethyl-3-cephem-4-carboxylic acid derivatives, showcasing the potential for further therapeutic development.

Career Highlights

Throughout his career, Herman H Grootveld has collaborated with notable companies such as Gist-brocades N.V. and Kalter, Jan. His work in these organizations has allowed him to cultivate his skills as an innovator and researcher in pharmaceutical chemistry.

Collaborations

Grootveld has worked alongside esteemed colleagues including Everardus J Leenderts and Hendrik A Witkamp. Their collaborations have contributed to significant advancements in the field, reflecting a commitment to fostering innovation in their respective projects.

Conclusion

Herman H Grootveld stands as a testament to the spirit of innovation within the pharmaceutical industry. With his five patents focusing on cephalosporin derivatives, he continues to push the boundaries of medical research and development. His career reflects a dedication to improving health outcomes through innovative solutions, establishing him as a respected inventor in his field.