East Windsor, NJ, United States of America

Hartmuth C Kolb

USPTO Granted Patents = 13 (Patent Applications = 2)

Average Co-Inventor Count = 3.6

ph-index = 2

Forward Citations = 13(Granted Patents)

Location History:

East Windsor, NY (US) (2003)
East Windsor, NJ (US) (2002 - 2004)
Marina Del Rey, CA (US) (2007)
San Diego, CA (US) (2005 - 2024)

Company Filing History:

7 out of 86

Lexicon Pharmaceuticals, Inc.

patents

4 out of 2,076

Janssen Pharmaceutica Nv

patents

1 out of 102

Lexicon Genetics Corporation

patents

4. 1 out of 1

Coelacanth Corporation

patent

Years Active: 2002-2024

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13 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12006302 - Tau PET imaging ligands (2024-06-11),

2. 11168068 - Tau PET imaging ligands (2021-11-09),

3. 10976325 - Assays to detect neurodegeneration (2021-04-13),

4. 10591492 - Assays to detect neurodegeneration (2020-03-17),

5. 7300949 - Thiazolopyrazoles and methods of their use (2007-11-27),

6. 7179827 - Thiazoles and methods of their use (2007-02-20),

7. 6951946 - Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates (2005-10-04),

8. 6891068 - Water as promoter in the nucleophilic substitution of chloride (2005-05-10),

9. 6806380 - Modified safe and efficient process for the environmentally friendly synthesis of imidoesters (2004-10-19),

10. 6713514 - PPAR-&ggr; agonists as agents for the treatment of type II diabetes (2004-03-30),

11. 6642390 - One step synthesis of 1,2,3-triazole carboxylic acids (2003-11-04),

12. 6562944 - Amide library formation using a “by-product-free” activation/coupling sequence (2003-05-13),

13. 6451918 - Sulfonyl linker for the creation of libraries via immobilization of amines (2002-09-17),

Title: Hartmuth C Kolb: Innovator in Tau PET Imaging Ligands

Introduction

Hartmuth C Kolb is a prominent inventor based in East Windsor, NJ (US), known for his significant contributions to the field of medical imaging. He holds a total of 13 patents, showcasing his innovative spirit and dedication to advancing technology in healthcare.

Latest Patents

Among his latest inventions are novel, selective radiolabelled tau ligands that are instrumental in imaging and quantifying tau aggregates using positron-emission tomography (PET). These tau PET imaging ligands are designed to enhance the understanding of tau pathology in various neurodegenerative diseases. The invention also encompasses compositions that include these compounds, processes for their preparation, and their application for imaging tissues or subjects, both in vitro and in vivo.

Career Highlights

Throughout his career, Hartmuth has worked with notable companies such as Lexicon Pharmaceuticals, Inc. and Janssen Pharmaceutica NV. His work in these organizations has contributed to the development of innovative solutions in the pharmaceutical and medical imaging sectors.

Collaborations

Hartmuth has collaborated with esteemed colleagues, including Zhi-Cai Shi and Ramanaiah C Kanamarlapudi, further enhancing the impact of his research and inventions.

Conclusion

Hartmuth C Kolb's contributions to the field of tau PET imaging ligands exemplify his commitment to innovation in medical technology. His work continues to influence advancements in imaging techniques, ultimately benefiting the understanding and treatment of neurodegenerative diseases.

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2 patents pending:

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