The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2021
Filed:
Jan. 24, 2020
Applicant:
Janssen Pharmaceutica NV, New Brunswick, NJ (US);
Inventors:
Hartmuth Christian Kolb, San Diego, CA (US);
Gallen Triana-Baltzer, San Diego, CA (US);
John Randall Slemmon, West Windsor, NJ (US);
Assignee:
Janssen Pharmaceutica NV, Beerse, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C12Q 1/48 (2006.01); G01N 33/573 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); C12Q 1/485 (2013.01); G01N 33/573 (2013.01); G01N 2440/14 (2013.01); G01N 2800/2821 (2013.01); G01N 2800/2828 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01); G01N 2800/56 (2013.01);
Abstract
Methods of measuring the amount of singly- or multiply-phosphorylated p217+ tau protein in a sample are provided. Methods of detecting or diagnosing tauopathies, methods of determining the effectiveness of a treatment of a tauopathy, and methods of determining whether a subject is suitable for anti-p217+ tau antibody therapy are also provided. Also described are antibodies for use in the methods and kits comprising the antibodies.