Hao-yang Mi

Title: Innovations of Hao-yang Mi in Vascular Grafts

Introduction

Hao-yang Mi is a prominent inventor based in Madison, WI (US), known for his significant contributions to the field of biomedical engineering. He has been awarded 3 patents for his innovative work, particularly in the development of advanced vascular grafts.

Latest Patents

One of his latest patents is titled "Wavy multi-component vascular grafts with biomimetic mechanical properties, antithrombogenicity, and endothelial cell affinity." This invention discloses novel wavy, multi-component vascular grafts (WMVGs) that feature a wavy inner layer of rigid biopolymer fibers and an outer layer of elastic biopolymer fibers. The method for preparing WMVGs involves electrospinning using a specially assembled collector. The fabricated WMVGs closely mimic the non-linear tensile stress-strain relationship of native blood vessels and demonstrate sufficient mechanical strength for implantation.

Another significant patent by Hao-yang Mi is "Promoting endothelial cell affinity and antithrombogenicity of polytetrafluoroethylene (PTFE) by mussel-inspired modification and RGD/heparin grafting." This patent discloses methods for modifying a substrate with a hydrophobic surface, resulting in modified hydrophobic substrates that improve cell affinity and antithrombogenicity.

Career Highlights

Hao-yang Mi is associated with the Wisconsin Alumni Research Foundation, where he continues to advance his research and innovations in the field of vascular grafts. His work has garnered attention for its potential applications in medical devices and treatments.

Collaborations

Hao-yang Mi collaborates with Lih-Sheng Turng, contributing to the advancement of their shared research interests in biomedical engineering.

Conclusion

Hao-yang Mi's innovative work in the development of vascular grafts showcases his commitment to improving medical technology. His patents reflect a deep understanding of biomimetic design and its applications in healthcare.