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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12251496 B1

PDFFull Text
Date of Patent:
Mar. 18, 2025

Filed:

May. 30, 2019

Wavy multi-component vascular grafts with biomimetic mechanical properties, antithrombogenicity, and endothelial cell affinity

Applicant:

Wisconsin Alumni Research Foundation, Madison, WI (US);

Inventors:

Lih-Sheng Turng, Madison, WI (US);

Hao-Yang Mi, Madison, WI (US);

Assignee:

Wisconsin Alumni Research Foundation, Madison, WI (US);

Attorney:

Sandberg Phoenix & von Gontard

Primary Examiner:

Melissa S Mercier

Assistant Examiner:

Caralynne E Helm

Int. Cl.
CPC ...
A61L 27/50 (2006.01); A61F 2/06 (2013.01); A61L 27/18 (2006.01); A61L 27/20 (2006.01); A61L 27/24 (2006.01); A61L 27/26 (2006.01); A61L 27/38 (2006.01); A61L 27/48 (2006.01); B32B 5/26 (2006.01); D01D 5/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/507 (2013.01); A61F 2/06 (2013.01); A61L 27/18 (2013.01); A61L 27/20 (2013.01); A61L 27/24 (2013.01); A61L 27/26 (2013.01); A61L 27/3808 (2013.01); A61L 27/3826 (2013.01); A61L 27/3834 (2013.01); A61L 27/3886 (2013.01); A61L 27/48 (2013.01); B32B 5/26 (2013.01); D01D 5/0007 (2013.01); A61F 2210/0076 (2013.01); A61F 2240/001 (2013.01);
Abstract

Disclosed herein are novel wavy, multi-component vascular grafts (WMVGs) with a wavy inner layer of rigid biopolymer fibers and an outer layer of elastic biopolymer fibers and a method for preparing WMVGs via electrospinning using a special assembled collector. The fabricated WMVGs closely mimic the non-linear tensile stress-strain relationship of native blood vessels and showed sufficient mechanical strength needed for implantation.

Find Patent Forward Citations

Turng, Lih-Sheng. (2025). Wavy multi-component vascular grafts with biomimetic mechanical properties, antithrombogenicity, and endothelial cell affinity (U.S. Patent No. 12251496). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12251496

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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