Wisconsin Alumni Research Foundation

Hao-yang Mi

Lih-Sheng Turng

Disclosed herein are novel wavy, multi-component vascular grafts (WMVGs) with a wavy inner layer of rigid biopolymer fibers and an outer layer of elastic biopolymer fibers and a method for preparing WMVGs via electrospinning using a special assembled collector. The fabricated WMVGs closely mimic the non-linear tensile stress-strain relationship of native blood vessels and showed sufficient mechanical strength needed for implantation.

Wavy multi-component vascular grafts with biomimetic mechanical properties, antithrombogenicity, and endothelial cell affinity

Disclosed herein are methods for modifying a substrate having a hydrophobic surface. Also disclosed are modified hydrophobic substrates. The modified hydrophobic substrates and methods disclosed herein advantageously improve cell affinity and antithrombogenicity of hydrophobic surfaces.

Growing community of inventors

Madison, WI, United States of America

Hao-yang Mi