Provincia de Buenos Aires, Argentina

Guillermo Daniel Mazzolini

USPTO Granted Patents = 2 

 

Average Co-Inventor Count = 3.7

ph-index = 1


Location History:

  • Provincia de Buenos Aires, AR (2019)
  • Garin, AR (2021)

Company Filing History:


Years Active: 2019-2021

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2 patents (USPTO):Explore Patents

Title: Guillermo Daniel Mazzolini: Innovator in Cancer Treatment

Introduction

Guillermo Daniel Mazzolini is a notable inventor based in Provincia de Buenos Aires, Argentina. He has made significant contributions to the field of cancer treatment through his innovative research and patented inventions. With a total of 2 patents, Mazzolini's work focuses on enhancing the efficacy of treatments for various types of cancer.

Latest Patents

Mazzolini's latest patents include groundbreaking compositions and methods aimed at increasing mesenchymal stromal cell migration to tumors. This application is particularly relevant for treating subjects with cancer, specifically targeting hepatocellular carcinoma (HCC). The methods involve stimulating mesenchymal stromal cells (MSCs) with a recombinant autocrine motility factor (rAMF) to enhance their migration to tumor sites. Additionally, he has developed methods to improve the adhesion of MSCs to endothelial cells using rAMF, which may include therapeutic agents such as anti-tumor agents.

Another significant patent by Mazzolini identifies SPARC (secreted protein, acidic and rich in cysteine) as a new therapeutic target for treating acute liver failure. This invention allows for the development of strategies to protect the liver from damage in patients suffering from fulminant hepatitis. The treatment involves administering agents that inhibit the expression of SPARC or interfere with its biological function.

Career Highlights

Throughout his career, Mazzolini has worked with esteemed organizations such as the National Scientific and Technical Research Council (CONICET) and Inis Biotech LLC. His research has been pivotal in advancing the understanding and treatment of liver-related diseases and cancer.

Collaborations

Mazzolini has collaborated with notable colleagues, including Mariana Gabriela Garcia and Juan Bayo. These partnerships have contributed to the success of his research and the development of his patents.

Conclusion

Guillermo Daniel Mazzolini is a distinguished inventor whose work in cancer treatment and liver health has the potential to significantly impact medical science. His innovative patents reflect a commitment to improving patient outcomes and advancing therapeutic strategies.

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