The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 16, 2021
Filed:
Feb. 09, 2018
Consejo Nacional DE Investigaciones Cientificas Y Tecnicas (Conicet), Caba, AR;
Asociacion Civil DE Estudios Superiores, Pilar, AR;
Inis Biotech Llc, Milford, DE (US);
Guillermo Daniel Mazzolini, Garin, AR;
Mariana Gabriela Garcia, Munro, AR;
Juan Bayo, Belen de Escobar, AR;
Consejo National de Investigaciones Cientificas y Tecnicas (CONICET), Buenos Aires, AR;
Abstract
The present application is directed to compositions and methods for treating a subject with cancer and/or increasing migration of a mesenchymal stromal cells (MSCs) stimulated with a recombinant autocrine motility factor (rAMF) to a tumor or a tumor cell, e.g. hepatocellular carcinoma (HCC). In addition, methods for increasing adhesion of MSCs to endothelial cells with rAMF are disclosed. In some embodiments, the MSCs comprise a therapeutic agent, e.g., an anti-tumor agent.